Pangrol 20,000 – High-Strength Pancreatic Enzyme Support for Digestive Health
Enteric-Coated Pancreatin Capsules for Improved Fat, Protein & Carbohydrate Absorption
Pangrol 20,000 is a pancreatic enzyme replacement therapy (PERT) containing pancreatin with high lipase activity (20,000 units), designed to support proper digestion in individuals with exocrine pancreatic insufficiency (EPI).
✔ Breaks down fats, proteins, and carbohydrates
✔ Reduces bloating, gas, and fatty stools
✔ Improves nutrient absorption and overall digestion
✔ Enteric-coated minimicrospheres ensure targeted release in the small intestine
Indications for Use:
• Chronic pancreatitis
• Cystic fibrosis (CF)
• Pancreatic surgery or resection
• Pancreatic cancer-related insufficiency
• Digestive enzyme deficiency from other GI conditions
Why Choose Pangrol 20,000?
✅ High enzyme concentration – ideal for moderate to severe pancreatic insufficiency
✅ Minimicrosphere technology – ensures uniform distribution in chyme
✅ Well-tolerated, non-systemic action – enzymes act only in the gut
✅ Improves quality of life for patients with fat digestion problems
Recommended Dosage (Adults):
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Usual starting dose: 1–2 capsules per main meal, 1 capsule with snacks
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Swallow whole – do not crush or chew (to protect enzyme coating)
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Individual dosage adjusted based on fat content of meals and clinical response
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Take with meals or immediately after for optimal effect
⚠ Important Safety Notes:
• Not suitable for individuals with porcine protein allergy
• High doses may cause intestinal narrowing (fibrosing colonopathy) – especially in cystic fibrosis patients
• Drink plenty of fluids during enzyme therapy
• Not for use in acute pancreatitis
Mechanism of Action:
• Lipase, amylase, and protease in pancreatin mimic natural enzymes
• Break down fats into fatty acids, starches into sugars, and proteins into amino acids
• Promotes proper nutrient absorption in the small intestine
Patient Tips:
• Always take with meals
• Do not store in humid environments – keep container tightly closed
• Enzyme therapy is lifelong for many pancreatic conditions
• Regular follow-up may be needed to assess dosing and vitamin levels
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