Although there is a significant difference between the two, they are often confused. Vitamin B9 is an essential nutrient that occurs naturally as folate. Folate refers to many forms of vitamin B-9. These include folic acid, dihydrofolate (DHF), 5-methyltetrahydrofolate (5-MTHF), and others. Folate plays a key role in new cell growth and DNA formation. Its low levels tend to be associated with high levels of homocysteine, birth defects in the fetus of pregnant women and other civilizational diseases.
Unlike folate, not all the folic acid you consume is converted to the active form of vitamin B9 = 5-MTHF. Folic acid must be converted in the liver to the active form methyl folate. However, this metabolic process does not work in some individuals and therefore unmetabolized folic acid can remain in the bloodstream and cause health problems. The problem of folic acid metabolism is sometimes aggravated by the fact that it is added to foods such as baked goods, pasta or breakfast cereals.
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