Thiocodin (15 mg/300 mg, 16 tablets) – Codeine-Based Antitussive Combination Drug
Composition and Mechanism of Action
Thiocodin is a combination medication containing two active ingredients:
- Codeine phosphate (15 mg) – An opioid alkaloid that suppresses the cough reflex in the medulla oblongata
- Terpin hydrate (300 mg) – An expectorant that stimulates bronchial gland secretion
The drug provides dual action:
✔ Antitussive (due to codeine)
✔ Expectorant (due to terpin hydrate)
Indications for Use
- Dry, debilitating cough caused by:
- Acute respiratory infections
- Tracheitis
- Bronchitis
- Pleurisy
- Preparation for bronchoscopy
Dosage and Administration
- Adults: 1 tablet 2-3 times daily
- Adolescents (12+ years): ½ tablet 2-3 times daily
- Maximum daily dose:
- Adults – 4 tablets (60 mg codeine)
- Adolescents – 2 tablets (30 mg codeine)
- Duration of treatment: No longer than 5 days
Special Precautions
⚠ Contraindications:
- Children under 12 years
- Asthma
- Respiratory failure
- Pregnancy and breastfeeding
- Concurrent use with MAO inhibitors
⚠ Side Effects:
- Constipation
- Drowsiness
- Nausea
- With prolonged use – risk of dependence
Drug Interactions
- Potentiates effects of:
- Sedatives
- Hypnotics
- Alcohol
- Incompatible with:
- Adsorbents (activated charcoal)
- Antidiarrheal medications
Storage Conditions
- Store at temperatures below 25°C (77°F)
- Shelf life: 3 years
- Prescription-only medication
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